|RNAiONE(TM) - approaching 100% knockdown|
Rational algorithm-based design of shRNA sequences has been successfully used for identification of active shRNA sequences. However knockdown efficiency of these sequences is generally 70% or less, and so only leads to partial gene knockdown,calling into question the validity of results.
SIRION Biotech`s core competence lies in the development of high efficiency shRNAs through the proprietary RNAiONE™platform.
Fields of Application
- whenever near quantitative knockdowns are needed
- loss of gene studies
- target identification & validation
- ON-targetcontrol cell models
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