References

Application Notes

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Whitepaper: 3D microtissue models for oncology research
Jointly developed by SIRION BIOTECH GmbH and InSphero AG
By Dr. Christian Thirion, CEO and Co-Founder of SIRION BIOTECH GmbH
 

Publications

1. Javier Carbajo-Lozoya, Marcel A. Müller, Stephan Kallies, Volker Thiel, Christian Drosten, Albrecht von Brunn.

   Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV- 229 E is inhibited by the drug FK506.
   

   Received 3 January 2012. Revised 31 January 2012. Accepted 3 February 2012. Available online 10 February 2012.

2. Nawroth R, Stellwagen F, Schulz WA, Stoehr R, Hartmann A, Krause BJ, Gschwend JE, Retz M.
   S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.
   PLoS One. 2011 Nov 15;6(11):e27509. Epub 2011 Nov 15.
3. Liebl J, Weitensteiner SB, Vereb G, Takács L, Fürst R, Vollmar AM, Zahler S.
   Cyclin-dependent kinase 5 regulates endothelial cell migration and angiogenesis.
   J Biol Chem. 2010 Nov 12;285(46):35932-43. Epub 2010 Sep 7.
4. Fischer I, Jeschke U, Friese K, Daher S, Betz AG.
   The role of galectin-1 in trophoblast differentiation and signal transduction.
   J Reprod Immunol. 2011 Jun;90(1):35-40. Epub 2011 May 31.
5. Mutze K, Langer R, Schumacher F, Becker K, Ott K, Novotny A, Hapfelmeier A, Höfler H, Keller G.
   DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
   Eur J Cancer. 2011 Aug;47(12):1817-25. Epub 2011 Mar 31.
6. Cotter L, Özçelik M, Jacob C, Pereira J.A, Locher V, Baumann R, Relvas J.B, Suter U & Tricaud N.
   Dlg1-PTEN Interaction Regulates Myelin Thickness to Prevent Damaging Peripheral Nerve Overmyelination.
   Science 268:1415-18 (2010).
7. Özçelik M, Cotter L, Jacob C, Pereira J.A, Relvas J.B, Suter U and Tricaud N.
   Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.
   J. Neurosci. 30(11): 4120-31 (2010).
8. Glasmacher E, Hoefig KP, Vogel KU, Rath N, Du L, Wolf C, Kremmer E, Wang X, Heissmeyer V.
   Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.
   Nat Immunol. 2010 Aug;11(8):725-33. Epub 2010 Jul 18. PMID: 20639877