Application Notes

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Whitepaper: 3D microtissue models for oncology research
Jointly developed by SIRION BIOTECH GmbH and InSphero AG
By Dr. Christian Thirion, CEO and Co-Founder of SIRION BIOTECH GmbH
 

Publications

1. Liebl J, Weitensteiner SB, Vereb G, Takács L, Fürst R, Vollmar AM, Zahler S.
   Cyclin-dependent kinase 5 regulates endothelial cell migration and angiogenesis.
   J Biol Chem. 2010 Nov 12;285(46):35932-43. Epub 2010 Sep 7.
2. Fischer I, Jeschke U, Friese K, Daher S, Betz AG.
   The role of galectin-1 in trophoblast differentiation and signal transduction.
   J Reprod Immunol. 2011 Jun;90(1):35-40. Epub 2011 May 31.
3. Mutze K, Langer R, Schumacher F, Becker K, Ott K, Novotny A, Hapfelmeier A, Höfler H, Keller G.
   DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
   Eur J Cancer. 2011 Aug;47(12):1817-25. Epub 2011 Mar 31.
4. Cotter L, Özçelik M, Jacob C, Pereira J.A, Locher V, Baumann R, Relvas J.B, Suter U & Tricaud N.
   Dlg1-PTEN Interaction Regulates Myelin Thickness to Prevent Damaging Peripheral Nerve Overmyelination.
   Science 268:1415-18 (2010).
5. Özçelik M, Cotter L, Jacob C, Pereira J.A, Relvas J.B, Suter U and Tricaud N.
   Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.
   J. Neurosci. 30(11): 4120-31 (2010).
6. Glasmacher E, Hoefig KP, Vogel KU, Rath N, Du L, Wolf C, Kremmer E, Wang X, Heissmeyer V.
   Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.
   Nat Immunol. 2010 Aug;11(8):725-33. Epub 2010 Jul 18. PMID: 20639877