Discovery and Preclinical Services
- Vector feasibility control for small and large scale manufacturing
- Customized development, manufacturing & QC packages for R&D and preclinical studies
- Full service package: from cDNA synthesis to particles manufacture and QC
- Vector productivity assessment prior to large-scale manufacture
AAV Capsid Engineering
- AAV Evolution
- Optimized capsids for gene therapy
- Retargeted AAV capsids using nanobodies (coming soon)
Cell & Gene Therapy Clinical Support
- In-depth analysis and consulting of CGT projects for improved efficacy and patient safety
- Selection of viral vector platforms
- Development of clinically compliant viral vector design
- Therapeutic payload cassette optimization for efficacious and safe expression profile
- Process development for optimal manufacturing productivity and negligible impurity levels
- PoC and biodistribuition studies of the lead candidate batches in large animals with a CRO network
Technology Licensing
- LentiBOOST® transduction enhancer with proven clinical success
- BAC technology & Ad19a/64 license opportunities for R&D and clinical applications
GMP Alliances
- Established CDMO network
- GMP-compliant lead vector plasmid.
- GMP-compliant manufacturing plasmids (coming soon).
- In development: GMP-compliant process transfer and validated assay transfer to CDMO