Uncover the best possible shRNA sequence against your gene target
Rational algorithm-based design of shRNA sequences has been successfully used for identification of active shRNA sequences. However knockdown efficiency of these sequences is generally 70% or less, and so only leads to partial gene knockdown – calling into question the validity of its results.
RNAiONE™ enables you to uncover the most efficient shRNA squence against any given target. Its results are fully translatable to SIRION Biotech`s viral vector platform and cell model generation service.
Fields of Application
- Whenever near quantitative knockdowns are needed
- Loss of gene studies
- Target identification & validation
- ON-target-control cell models
- Knockdown guarantee of > 80% on mRNA level
- Results fully translatable with viral vector design & cell model generation
- Validated shRNA in less than 3 weeks
Project statistics & Customer Satisfaction Guarantee
Over the years SIRION Biotech has developed its base technology into an art: in 80% of recent projects SIRION Biotech managed to identify shRNAs with knockdown results of above 90%. Such experience makes it possible to issue warranties with its quotes.
Contact us to discover more.