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Uncover the best possible shRNA sequence against your gene target

Rational algorithm-based design of shRNA sequences has been successfully used for identification of active shRNA sequences. However knockdown efficiency of these sequences is generally 70% or less, and so only leads to partial gene knockdown – calling into question the validity of its results.

RNAiONE™ enables you to uncover the most efficient shRNA squence against any given target. Its results are fully translatable to SIRION Biotech`s viral vector platform.

Fields of Application

  • Whenever near quantitative knockdowns are needed
  • Loss of gene studies
  • Target identification & validation
  • ON-target-control cell models

SIRION`s benefits

  • Knockdown guarantee of > 80% on mRNA level
  • Results fully translatable into viral vector engineering
  • Validated shRNA in less than 3 weeks

Project statistics & Customer Satisfaction Guarantee

Over the years SIRION Biotech has developed its base technology into an art: in 80% of recent projects SIRION Biotech managed to identify shRNAs with knockdown results of above 90%. Such experience makes it possible to issue warranties with its quotes.

Contact us to discover more.